1. Chalut, C., Botella, L., de Sousa-D'Auria, C., Houssin, C. & Guilhot, C. (2006).
The non redundant roles of two 4'-phosphopantetheinyl transferases in vital processes of Mycobacteria.
Proc. Natl. Acad. Sci. (USA), 103: 8511-8516.

2. Fernandez, P., Saint-Joanis, B., Barilone, N., Jackson, M., Gicquel, B, Cole, S.T., & Alzari, P.M. (2006)
The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth.
J. Bacteriol. 188: 7778 - 7784.

3. Henriksson, L. M., Björkelid, C., Mowbray, S. L., & Unge, T. (2006)
The 1.9 Å resolution structure of the Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target.
Acta Crystallographica D, D62: 807-813.

4. Johansson, P., Castell, A., Jones, T. A., & Bäckbro, K. (2006)
Structure and function of Rv0130, a conserved hypothetical protein from Mycobacterium tuberculosis
Protein Science, 15: 2300-2309.

5. McLean, K.J., Clift, D., Lewis, D.G., Sabri, M., Balding, P.R., Sutcliffe, M.J., Leys, D. & Munro, A.W. (2006).
The preponderance of P450s in the Mycobacterium tuberculosis genome.
Trends Microbiol. 14: 220-228.

6. McLean, K.J., Dunford, A.J., Sabri, M., Neeli, R., Girvan, H.M., Balding, P.R., Leys, D., Seward, H.E., Marshall, K.R. and Munro. A.W. (2006).
CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: Towards deconvoluting enzymology of P450 systems in a human pathogen.
Biochem. Soc. Trans. 34: 1178 - 1182.

7. McLean, K.J., Warman, A.J., Seward, H.E., Marshall, K.R., Girvan, H.M., Cheesman, M.R., Waterman, M.R. & Munro, A.W. (2006).
Biophysical characterization of the sterol demethylase P450 (CYP51) from Mycobacterium tuberculosis, its cognate ferredoxin (Fdx) and their interactions.
Biochemistry 45: 8427-8443.

8. Prado, S., Ledeit, H., Michel, S., Koch, M., Darbord, J.C., Cole, S.T., Tillequin, F.; Brodin, P. (2006
Benzofuro[3,2-f]benzopyrans: A New Class of Antitubercular Agents.
Bioorg. Med. Chem. 14: 5423-5428.

9. Saint-Joanis, B., Demangel, C., Jackson, M., Brodin, P., Marsollier, L., Boshoff, H., & Cole, S.T. ( 2006)
Inactivation of Rv2525c, a Substrate of the Twin Arginine Translocation (Tat) System of Mycobacterium tuberculosis, Increases β-Lactam Susceptibility and Virulence
J. Bacteriol. 188: 6669-6679.

10. Seward, H.E., Roujeinikova, A., McLean, K.J., Munro, A.W. & Leys, D. (2006).
Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode.
J. Biol. Chem. 281: 39437 - 39443.

11. Bellinzoni, M., Wehenkel, A., Shepard, W. & Alzari, P.M. (2007)
Insights into the catalytic mechanism of PPM Ser/Thr phosphatases from the atomic resolution structures of a mycobacterial enzyme.
Structure, in press.

12. Brosch, R. & Vincent, V. (2007)
Cutting-edge science and the future of tuberculosis control.
Bulletin of the World Health Organization 85: 410-412.

13. de Jonge, M.I., Pehau-Arnaudet, G., Fretz, M.M., Romain, F., Bottai, D., Brodin, P., Honoré N., Marchal, G., Jiskoot, W., England, P., Cole, S.T., & Brosch, R. (2007)
ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity.
J. Bacteriol. 189: 6028-6034.

14. Dunford, A.J., McLean, K.J., Sabri, M., Seward, H.E., Heyes, D.J., Scrutton, N.S. & Munro, A.W. (2007).
Rapid P450 heme iron reduction by laser photoexcitation of Mycobacterium tuberculosis CYP121 and CYP51B1: Analysis of CO complexation reactions and reversibility of the P450/P420 equilibrium.
J. Biol. Chem. (submitted).

15. Guerin, M.E., Kordulakova, J., Schaeffer, F., Svetlikova, Z., Buschiazzo, A., Giganti, D., Gicquel, B., Mikusova, K., Jackson M. and Alzari, P.M. (2007)
Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria.
J. Biol. Chem, May 16 in press. PMID: 17510062

16. Henriksson, L.M., Unge, T., Carlsson, J., Åqvist, J., Mowbray, S.L. & Jones, T.A. (2007)
Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase provide new insights into catalysis.
J. Biol. Chem. In press

17. Janin, Y.L. (2007)
Antituberculosis drugs: Ten years of research.
Bioorganic & Medicinal Chemistry. In press.

18. Lucarelli, D., Russo, S., Garman, E., Milano, A., Meyer-Klaucke, W., & Pohl, E. (2007)
Crystal Structure and Function of the Zinc Uptake Regulator FurB from Mycobacterium tuberculosis.
J. Biol. Chem. 282: 9914 - 9922.

19. Maciag, A., Dainese, E., Rodriguez, E.G., Milano, A., Provvedi, R., Pasca, M.R., Smith, I., Palù, G., Riccardi,G., and Manganelli, R. (2007)
Global analysis of Mycobacterium tuberculosis Zur (FurB) regulon.
J. Bacteriol. 189: 730 - 740.

20. McLean, K.J., Dunford, A.J., Neeli, R., Driscoll, M.D and Munro, A.W. (2007).
Structure, function and drug targeting in Mycobacterium tuberculosis cytochrome P450 systems.
Arch. Biochem. Biophys. (in press).

21. Munro, A.W., Girvan, H.M. and McLean, K.J. (2007).
Cytochrome P450-redox partner fusion enzymes.
Biochim. Biophys. Acta 1770, 345-359.

22. Prado, S., Janin Y.L., Saint-Joanis, B., Brodin, P., Michel, S., Koch, M., Cole, S.T., Tillequin, F., & Bost, P.E. (2007)
Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues.
Bioorg Med Chem. 15: 2177-2186.

23. Prado, S., Toum, V., Saint-Joanis, B., Michel, S., Koch, M., Cole, S.T., Tillequin, F., & Janin Y.L., (2007)
Antimycobacterial Benzofuro[3,2-f]chromenes from a 5-Bromochromen-6-ol.
J. Synthetic Organic Chem. 10: 1566 - 1570.

24. Sacco, E., Legendre, V., Laval, F., Zerbib, D., Montrozier, H., Eynard, N., Guilhot, C., Daffé, M., & Quémard, A (2007).
Rv3389C from Mycobacterium tuberculosis, a member of the (R)-specific hydratase/dehydratase family.
Biochim. Biophys. Acta- Proteins and Proteomics 1774: 303-311.

25. Sacco, E., Suarez Covarrubias, Adrian., O'Hare, H.M., Carroll, P., Eynard, N., Jones, T.A., Parish, T., Daffé, M., Bäckbro, K., & Quémard, K. (2007)
The missing piece of the type II Fatty Acid Synthase system from Mycobacterium tuberculosis.
PNAS Submitted.

26. Alvey, L.; Prado, S.; Huteau, H.; Saint-Joanis, B.; Michel, S.; Koch, M.; Cole, S.T.; Tillequin, F.; Janin, Y.L. (2008)
A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial.
Bioorg. Med. Chem.16: 8264-8272.

1. Arand, M., Cronin, A., Adamska, M. and Oesch, F. (2005)
Epoxide hydrolases: structure, function, mechanism, and assay.
Methods Enzymol 400: 569-588.

2. Johansson, P., Unge, T., Cronin, A., Arand, M., Bergfors, T., Jones, T. A. & Mowbray, S. L. (2005)
Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function.
J. Mol. Biol. 351: 1048-1056.

3. McLean, K.J., Sabri, M., Marshall, K.R., Lawson, R.J., Lewis, D.G., Clift, D., Balding, P.R., Dunford, A.J., Warman, A.J., McVey, J.P., Quinn, A.M., Sutcliffe, M.J., Scrutton, N.S., & Munro, A.W. (2005).
Biodiversity of cytochrome P450 redox systems.
Biochem. Soc. Trans. 33, 796-801.

3. Mikusová, K., Belánová, M., Korduláková, J., Honda, K., McNeil, M., Mahapatra, S., Crick, D., Brennan, P. J. (2006)
Identification of a novel galactosyl transferase involved in biosynthesis of mycobacterial cell wall.
Journal of Bacteriology 188: 6592-6598.

4. van Loo, B., Kingma, J., Arand, M., Wubbolts, M. G. & Janssen, D. B. (2006)
Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis.
Appl Environ Microbiol 72: 2905-2917.